Rodrigo Valenzuela

Profesor Asistente

Nutricionista (Universidad de Chile)

Magister en Nutrición y Alimentos (Universidad de Chile) Doctor en Nutrición y Alimentos (Universidad de Chile)

+56 2 29786014

rvalenzuelab@med.uchile.cl

Docencia

Alimentos I y II

Seminario Alimentos y Nutrición

Higiene en la Producción de Alimentos

Calidad e Inocuidad Alimentaria

Planificación, Organización, Dirección y Control en Servicios de Alimentación Colectiva ​Genética y Nutrigenómica

Bioquímica Nutricional

Nutrición

Metodología de la Investigación

Bases Fisiológicas y Bioquímicas de la Nutrición

Lípidos aspectos químicos y Nutricionales

Línea(s) de Investigación

1. Metabolismo de lípidos y efectos citoprotectores

2. Metabolismo de ácidos grasos e interacción con el estrés oxidativo - mecanismos moleculares asociados al daño celular

Proyecto(s) vigente(s)

​Título: Recovery of marine phospholipids rich in ω-3 (EPA + DHA) fatty acids and high nutritional value from the residual fat fishmeal

Duración: 2014-2016

Financiamiento: Copec- UC Foundation

Investigador Principal: Rodrigo Valenzuela B

Institución albergante: Universidad de Chile

Rol en el proyecto: Investigador Principal

 

Título: Molecular mechanisms of the protection by oral administration of n-3 long chain polyunsaturated fatty acids and hydroxytyrosol against liver steatosis, oxidative stress, inflammation and insulin resistance induced by high fat diet in mice

Duracion: 2015-2017

Financiamiento: Fondecyt of Initiation 11140174

Investigador Principal: Rodrigo Valenzuela B

Institución albergante: Universidad de Chile

Rol en el proyecto: Investigador Principal

 

Titulo: Educational, socio-economic, neurological, psychological, nutritional, and family variables affecting the University Selection Test (PSU) achievement and later job status: A ninth-year follow-up study in a multicausal approach

Duración: 2015-2018

Financiamiento: FONDECYT Regular 1150524

Investigador Principal: Daniza Ivanovic M

Institución albergante: Universidad de Chile

Rol en el Proyecto: Co-investigador

Publicacion(es) destacada(s)

Rodrigo Valenzuela and Luis A. Videla (2011) The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity. Food Function. 3:644-648.

 

Rodrigo Valenzuela B., Juan G. Gormáz, Lilia Masson S, Pamela Cornejo Z, Alfonso Valenzuela B and Gladys Tapia O. (2012) Evaluation of hepatic bioconversion of α- linolenic acid (ALA) to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in rats fed oils from chia (Salvia hispánica) or rosa mosqueta (Rosa rubiginosa). Grasas y Aceites. 63:61-69. 

 

González-Mañán D, Tapia G, Gormaz JG, D'Espessailles A, Espinosa A, Masson L, Varela P, Valenzuela A, Valenzuela R*. (2012) Bioconversion of α-linolenic acid to n-3 LCPUFA and expression of PPAR-alpha, acyl coenzyme A oxidase 1 and carnitine acyl transferase I are incremented after feeding rats with α-linolenic acid-rich oils. Food Funct. Vol 3:765-772.

 

Rodrigo Valenzuela, Alejandra Espinosa, Daniel González, Amanda D’Espessailles, Virginia Fernández, Luis A. Videla and Gladys Tapia. (2012) N-3 Long-Chain Polyunsaturated Fatty Acid Supplementation Significantly Reduces Liver Oxidative Stress in High Fat Induced Steatosis. Plos One. 7, e46400.

 

Rodrigo Valenzuela*, Cynthia Barrera, José Miguel Ayala, Julio Sanhueza, Alfonso Valenzuela, Vegetable oils rich in alpha linolenic acid (ALA) allow a higher accretion of n-3 LCPUFA in the plasma, liver and adipose tissue of the rat (2014) Grasas y Aceites. 65, e26.

 

Gladys Tapia, Rodrigo Valenzuela, Alejandra Espinosa, Pamela Romanque, Camila Dossi, Daniel Gonzalez-Mañán, Luis A. Videla and Amanda D'Espessailles (2014). N-3 long-chain PUFA supplementation prevents high fat diet induced mouse liver steatosis and inflammation in relation to PPAR-α upregulation and NF-κB DNA binding abrogation. Mol Nutr Food Res. 58:1333-41.

 

Valenzuela R.*, Barrera R. C., González-Astorga M., Sanhueza C. J., Valenzuela B. A. (2014) Alpha linolenic acid (ALA) from Rosa canina, sacha inchi and chia oils may increase ALA accretion and its conversion into n-3 LCPUFA in diverse tissues of the rat. Food Funct. 25:1564-72.

 

Bascuñán KA, Valenzuela R, Chamorro R, Valencia A, Barrera C, Puigrredon C, Sandoval J, Valenzuela A. (2014) Polyunsaturated Fatty Acid composition of maternal diet and erythrocyte phospholipid status in chilean pregnant women. Nutrients. 7:4918-34.

 

Valenzuela R*, Barrera C, Espinosa A, Llanos P, Orellana P, Videla LA. (2015) Reduction in the desaturation capacity of the liver in mice subjected to high fat diet: Relation to LCPUFA depletion in liver and extrahepatic tissues. Prostaglandins Leukot Essent Fatty Acids. 98: 7-14.

 

Valenzuela R*, Bascuñán K, Chamorro R, Barrera C, Sandoval J, Puigrredon C, Parraguez G, Orellana P, Gonzalez V, Valenzuela A. (2015). Modification of Docosahexaenoic Acid Composition of Milk from Nursing Women Who Received Alpha Linolenic Acid from Chia Oil during Gestation and Nursing. Nutrients. 7, 6405-24.

 

Maria Catalina Hernandez-Rodas, Rodrigo Valenzuela* and Luis A. Videla. (2015). Relevant aspects of nutritional and dietary interventions in non-alcoholic fatty liver disease. Int. J. Mol. Sci. 16, 25168-25198.

 

Valenzuela R*, Espinosa A, Llanos P, Hernandez-Rodas MC, Barrera C, Vergara D, Romero N, Pérez F, Ruz M, Videla LA (2016). Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet. Food Funct. 7, 140 - 150

 

R. Valenzuela, M.C. Hernandez-Rodas, A. Espinosa, M.A. Rincón, N. Romero, C. Barrera, M. Marambio, J. Vivero, A. Valenzuela (2016). Extra virgin olive oil reduces liver oxidative stress and tissue depletion of long chain polyunsaturated fatty acid produced by a high saturated fat diet in mice. Grasas & Aceites. 2, eI29.

 

Miguel Ángel Rincón-Cervera, Rodrigo Valenzuela*, María Catalina Hernandez-Rodas, Cynthia Barrera, Alejandra Espinosa, Macarena Marambio, Alfonso Valenzuela (2016). Vegetable oils rich in alpha linolenic acid increment hepatic n-3 LCPUFA, modulating the fatty acid metabolism and antioxidant response in rats. Prostaglandins Leukot Essent Fatty Acids. 111; 25-35.

 

Rincón-Cervera MA, Valenzuela R*, Hernandez-Rodas MC, Marambio M, Espinosa A, Mayer S, Romero N, Barrera M Sc C, Valenzuela A, Videla LA. Supplementation with antioxidant-rich extra virgin olive oil prevents hepatic oxidative stress and reduction of desaturation capacity in mice fed a high-fat diet: Effects on fatty acid composition in liver and extrahepatic tissues (2016.) Nutrition. 32: 1254-67.

 

Echeverría F, Ortiz M, Valenzuela R*, Videla L.A. Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging (2016). Prostaglandins Leukot Essent Fatty Acids. doi.org/10.1016/j.plefa.2016.10.001. En Prensa.  

CV in extenso

Departamento de Nutricion
Departamento de Nutricion
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Contacto

Departamento de Nutrición

Universidad de Chile

Tel: +56 2 29786136

Email: dirdenut@med.uchile.cl

Dirección

Av. Independencia 1027,

Independencia, Santiago, CHILE